SMO (SMOOTHENED TRANSMEMBRANE PROTEIN) INHIBITORS (VISMODEGIB) IN TREATMENT OF BASAL CELL CARCINOMA (BCC) OF OCULAR ADNEXA

Basal Cell Carcinoma (BCC) is one of the well spread malignant skin cancers. Eighty percent of it occurs in the head-neck area of which 20% in the eyelids. The major genes for BCC are: PTCH1 and PTCH2. PTCH1 supresses transmembrane Smoothened (SMO) protein, while PTCH2 have his role uncleared, but t...

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Bibliographic Details
Main Authors: Georgi Balchev, Chavdar Balabanov, Snezhana Murgova
Format: Article
Language:English
Published: Peytchinski Publishing 2020-04-01
Series:Journal of IMAB
Subjects:
Online Access:https://www.journal-imab-bg.org/issues-2020/issue2/JofIMAB-2020-26-2p3102-3106.pdf