SMO (SMOOTHENED TRANSMEMBRANE PROTEIN) INHIBITORS (VISMODEGIB) IN TREATMENT OF BASAL CELL CARCINOMA (BCC) OF OCULAR ADNEXA
Basal Cell Carcinoma (BCC) is one of the well spread malignant skin cancers. Eighty percent of it occurs in the head-neck area of which 20% in the eyelids. The major genes for BCC are: PTCH1 and PTCH2. PTCH1 supresses transmembrane Smoothened (SMO) protein, while PTCH2 have his role uncleared, but t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Peytchinski Publishing
2020-04-01
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Series: | Journal of IMAB |
Subjects: | |
Online Access: | https://www.journal-imab-bg.org/issues-2020/issue2/JofIMAB-2020-26-2p3102-3106.pdf |