Carbon Ion Radiotherapy: A Review of Clinical Experiences and Preclinical Research, with an Emphasis on DNA Damage/Repair

Compared to conventional photon-based external beam radiation (PhXRT), carbon ion radiotherapy (CIRT) has superior dose distribution, higher linear energy transfer (LET), and a higher relative biological effectiveness (RBE). This enhanced RBE is driven by a unique DNA damage signature characterized...

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Bibliographic Details
Main Authors: Osama Mohamad, Brock J. Sishc, Janapriya Saha, Arnold Pompos, Asal Rahimi, Michael D. Story, Anthony J. Davis, D.W. Nathan Kim
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/9/6/66