Lifespan regulation by evolutionarily conserved genes essential for viability.

Evolutionarily conserved mechanisms that control aging are predicted to have prereproductive functions in order to be subject to natural selection. Genes that are essential for growth and development are highly conserved in evolution, but their role in longevity has not previously been assessed. We...

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Bibliographic Details
Main Authors: Sean P Curran, Gary Ruvkun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1847696?pdf=render