Anti-tumor effects of rigosertib in high-risk neuroblastoma

Anti-tumor effects of rigosertib in high-risk neuroblastoma

High-risk neuroblastoma has a poor prognosis despite intense treatment, demonstrating the need for new therapeutic strategies. Here we evaluated the effects of rigosertib (ON-01910.Na) in preclinical models of high-risk neuroblastoma. Among several hundred cancer cell lines representing 24 tumor typ...

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Bibliographic Details
Main Authors: Katarzyna Radke, Karin Hansson, Jonas Sjölund, Magdalena Wolska, Jenny Karlsson, Javanshir Esfandyari, Kristian Pietras, Kristina Aaltonen, David Gisselsson, Daniel Bexell
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Translational Oncology
Subjects:
Neuroblastoma
Rigosertib
ON-01910
ON-01910.Na
Patient-derived xenografts
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321001418

Internet

http://www.sciencedirect.com/science/article/pii/S1936523321001418

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