BtubA-BtubB heterodimer is an essential intermediate in protofilament assembly.

BACKGROUND:BtubA and BtubB are two tubulin-like genes found in the bacterium Prosthecobacter. Our work and a previous crystal structure suggest that BtubB corresponds to alpha-tubulin and BtubA to beta-tubulin. A 1:1 mixture of the two proteins assembles into tubulin-like protofilaments, which furth...

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Bibliographic Details
Main Authors: Christopher A Sontag, Harvey Sage, Harold P Erickson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2746283?pdf=render