HFD and HFD-provoked hepatic hypoxia act as reciprocal causation for NAFLD via HIF-independent signaling

HFD and HFD-provoked hepatic hypoxia act as reciprocal causation for NAFLD via HIF-independent signaling

Abstract Background The occurrence of non-alcoholic fatty liver disease (NAFLD) is found to be higher in patients with obstructive sleep apnea (OSA), which is characterized by intermittent hypoxia. Activation of hypoxia-inducible factors has been shown in the development and progression of NAFLD, im...

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Bibliographic Details
Main Authors: Xiaofang Zhang, Caoxin Huang, Xuejun Li, Zhaoshui Shangguan, Wenjing Wei, Suhuan Liu, Shuyu Yang, Yijie Liu
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Gastroenterology
Subjects:
NAFLD
Hypoxia
HIF
Steatosis
Online Access:http://link.springer.com/article/10.1186/s12876-020-01515-5

Internet

http://link.springer.com/article/10.1186/s12876-020-01515-5

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