Arsenic Primes Human Bone Marrow CD34+ Cells for Erythroid Differentiation

Arsenic trioxide exhibits therapeutic effects on certain blood malignancies, at least partly by modulating cell differentiation. Previous in vitro studies in human hematopoietic progenitor cells have suggested that arsenic may inhibit erythroid differentiation. However, these effects were all observ...

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Bibliographic Details
Main Authors: Yuanyuan Zhang, Shasha Wang, Chunyan Chen, Xiao Wu, Qunye Zhang, Fan Jiang
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2015/751013