Strategies for informed sample size reduction in adaptive controlled clinical trials

Abstract Clinical trial adaptation refers to any adjustment of the trial protocol after the onset of the trial. The main goal is to make the process of introducing new medical interventions to patients more efficient. The principal challenge, which is an outstanding research problem, is to be found...

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Bibliographic Details
Main Author: Ognjen Arandjelović
Format: Article
Language:English
Published: SpringerOpen 2017-10-01
Series:EURASIP Journal on Advances in Signal Processing
Subjects:
RCT
Online Access:http://link.springer.com/article/10.1186/s13634-017-0510-z