Strategies for informed sample size reduction in adaptive controlled clinical trials
Abstract Clinical trial adaptation refers to any adjustment of the trial protocol after the onset of the trial. The main goal is to make the process of introducing new medical interventions to patients more efficient. The principal challenge, which is an outstanding research problem, is to be found...
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Format: | Article |
Language: | English |
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SpringerOpen
2017-10-01
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Series: | EURASIP Journal on Advances in Signal Processing |
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Online Access: | http://link.springer.com/article/10.1186/s13634-017-0510-z |