Evidence of a Demethylase-Independent Role for the H3K4-Specific Histone Demethylases in Aspergillus nidulans and Fusarium graminearum Secondary Metabolism

Evidence of a Demethylase-Independent Role for the H3K4-Specific Histone Demethylases in Aspergillus nidulans and Fusarium graminearum Secondary Metabolism

Fungi produce a plethora of secondary metabolites (SMs) involved in cellular protection, defense, and signaling. Like other metabolic processes, transcription of SM biosynthesis genes is tightly regulated to prevent an unnecessary use of resources. Genes involved in SM biosynthesis are usually physi...

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Bibliographic Details
Main Authors: Simone Bachleitner, Jens Laurids Sørensen, Agnieszka Gacek-Matthews, Michael Sulyok, Lena Studt, Joseph Strauss
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
KDM5
histone demethylase
secondary metabolism
Aspergillus nidulans
Fusarium graminearum
H3K4 methylation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01759/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01759/full

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