Evaluation of an injectable thermosensitive hydrogel as drug delivery implant for ocular glaucoma surgery.

Evaluation of an injectable thermosensitive hydrogel as drug delivery implant for ocular glaucoma surgery.

In this study, a biodegradable thermo-sensitive hydrogel from poly(trimethylene carbonate)15-F127-poly(trimethylene carbonate)15 (PTMC15-F127-PTMC15) was designed and evaluated as an injectable implant during ocular glaucoma filtration surgery in vivo and in vitro. Mitomycin C (MMC) was loaded into...

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Bibliographic Details
Main Authors: Lei Xi, Tao Wang, Feng Zhao, Qiongjuan Zheng, Xiaoning Li, Jing Luo, Ji Liu, Daping Quan, Jian Ge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4065085?pdf=render

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