Evaluation of an injectable thermosensitive hydrogel as drug delivery implant for ocular glaucoma surgery.

In this study, a biodegradable thermo-sensitive hydrogel from poly(trimethylene carbonate)15-F127-poly(trimethylene carbonate)15 (PTMC15-F127-PTMC15) was designed and evaluated as an injectable implant during ocular glaucoma filtration surgery in vivo and in vitro. Mitomycin C (MMC) was loaded into...

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Bibliographic Details
Main Authors: Lei Xi, Tao Wang, Feng Zhao, Qiongjuan Zheng, Xiaoning Li, Jing Luo, Ji Liu, Daping Quan, Jian Ge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4065085?pdf=render