Adjuvant chemotherapy for brain tumors delivered via a novel intra-cavity moldable polymer matrix.

INTRODUCTION:Polymer-based delivery systems offer innovative intra-cavity administration of drugs, with the potential to better target micro-deposits of cancer cells in brain parenchyma beyond the resected cavity. Here we evaluate clinical utility, toxicity and sustained drug release capability of a...

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Bibliographic Details
Main Authors: Cheryl V Rahman, Stuart J Smith, Paul S Morgan, Keith A Langmack, Phil A Clarke, Alison A Ritchie, Donald C Macarthur, Felicity R Rose, Kevin M Shakesheff, Richard G Grundy, Ruman Rahman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796488?pdf=render