Cystic fibrosis: model of pathogenesis based on the apical membrane potential
A simple model of cystic fibrosis (CF) is proposed, based on the apical membrane (ApM) potential. The ApM of epithelial cells is highly permeable to sodium and activation of CFTRs makes it permeable to chloride. Calculated ApM potentials of cells with activated cystic fibrosis transmembrane conducta...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Medical Association of Zenica-Doboj Canton
2015-02-01
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Series: | Medicinski Glasnik |
Subjects: | |
Online Access: | http://www.ljkzedo.ba/sites/default/files/Glasnik/12-01-feb2015/01%20Kurbel.pdf |