Investigation of a Novel LRP6 Variant Causing Autosomal-Dominant Tooth Agenesis

BackgroundThe low-density lipoprotein receptor-related protein 6 (LRP6) gene is a recently defined gene that is associated with the autosomal-dominant inherited tooth agenesis (TA). In the present study, a family of four generations having TA was recruited and subjected to a series of clinical, gene...

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Bibliographic Details
Main Authors: Yan-xia Huang, Chun-yan Gao, Chun-yan Zheng, Xu Chen, You-sheng Yan, Yong-qing Sun, Xing-yue Dong, Kai Yang, Dong-liang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.688241/full