Streamlined histone-based fluorescence lifetime imaging microscopy (FLIM) for studying chromatin organisation
Changes in chromatin structure are key determinants of genomic responses. Thus, methods that enable such measurements are instrumental for investigating genome regulation and function. Here, we report further developments and validation of a streamlined method of histone-based fluorescence lifetime...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-03-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/7/3/bio031476 |