Streamlined histone-based fluorescence lifetime imaging microscopy (FLIM) for studying chromatin organisation

Changes in chromatin structure are key determinants of genomic responses. Thus, methods that enable such measurements are instrumental for investigating genome regulation and function. Here, we report further developments and validation of a streamlined method of histone-based fluorescence lifetime...

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Bibliographic Details
Main Authors: Alice Sherrard, Paul Bishop, Melanie Panagi, Maria Beatriz Villagomez, Dominic Alibhai, Abderrahmane Kaidi
Format: Article
Language:English
Published: The Company of Biologists 2018-03-01
Series:Biology Open
Subjects:
ATM
Online Access:http://bio.biologists.org/content/7/3/bio031476