Different BCS Class II Drug-Gelucire Solid Dispersions Prepared by Spray Congealing: Evaluation of Solid State Properties and In Vitro Performances

Different BCS Class II Drug-Gelucire Solid Dispersions Prepared by Spray Congealing: Evaluation of Solid State Properties and In Vitro Performances

Delivery of poorly water soluble active pharmaceutical ingredients (APIs) by semi-crystalline solid dispersions prepared by spray congealing in form of microparticles (MPs) is an emerging method to increase their oral bioavailability. In this study, solid dispersions based on hydrophilic Gelucires&l...

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Bibliographic Details
Main Authors: Serena Bertoni, Beatrice Albertini, Nadia Passerini
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pharmaceutics
Subjects:
microparticles
spray chilling
spray cooling
Gelucire
semicrystalline solid dispersions
carbamazepine
Online Access:https://www.mdpi.com/1999-4923/12/6/548

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https://www.mdpi.com/1999-4923/12/6/548

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