zGrad is a nanobody-based degron system that inactivates proteins in zebrafish

zGrad is a nanobody-based degron system that inactivates proteins in zebrafish

The analysis of protein function is essential to modern biology. While protein function has mostly been studied through gene or RNA interference, more recent approaches to degrade proteins directly have been developed. Here, we adapted the anti-GFP nanobody-based system deGradFP from flies to zebraf...

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Bibliographic Details
Main Authors: Naoya Yamaguchi, Tugba Colak-Champollion, Holger Knaut
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
degron system
protein degradation
gene expression
Online Access:https://elifesciences.org/articles/43125

Internet

https://elifesciences.org/articles/43125

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