Chemotaxing neutrophils enter alternate branches at capillary bifurcations

Neutrophils mobilize rapidly and travel through the vasculature and microcirculation en masse in response to inflammatory stimuli. Here the authors use a microfluidic device and intravital microscopy to show neutrophils move through tissues in a highly ordered pattern, taking turns to file into alte...

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Bibliographic Details
Main Authors: Xiao Wang, Mokarram Hossain, Ania Bogoslowski, Paul Kubes, Daniel Irimia
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15476-6