Nanostructured liquid crystalline formulation as a remarkable new drug delivery system of anti-epileptic drugs for treating children patients

Purpose: Development of a new dosage-form of antiepileptic-drugs appropriated for children. Methods: Clonazepam (Cl) was formulated as cubosomal-gel (cub-gel) to be used as a patch reservoir through transdermal-route. Cubosomes prepared using glycerol-mono-oleate(GMO)/Pluronic-F127(PF127) mixture. A...

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Bibliographic Details
Main Authors: Hadel Abo El-Enin, Areej Hamed AL-Shanbari
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016418300835