Craniofacial Osteosarcoma—Pilot Study on the Expression of Osteobiologic Characteristics and Hypothesis on Metastasis

Background: Craniofacial osteosarcomas (COS) and extracranial osteosarcomas (EOS) show distinct clinical differences. COS show a remarkably lower incidence of metastases and a better survival. However, in contrast to EOS, they show a poor response to neoadjuvant chemotherapy. Tumor-associated macrop...

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Bibliographic Details
Main Authors: Manuel Weber, Stephan Söder, Janina Sander, Jutta Ries, Carol Geppert, Marco Kesting, Falk Wehrhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
M1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00745/full