Fruits of Rosa laevigata and its bio-active principal sitostenone facilitate glucose uptake and insulin sensitivity in hepatic cells via AMPK/PPAR-γ activation

Background: Fruits of Rosa laevigata Michx is commonly used in traditional Chinese medicine for treating of spleen deficiency, chronic diarrhea, and chronic urinary tract infection. Recently, fruits of R. laevigate have been shown to have renal protective effects in diabetic rats. However, up to now...

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Bibliographic Details
Main Authors: K.J. Senthil Kumar, Chun Lin, Yen-Hsueh Tseng, Sheng-Yang Wang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Phytomedicine Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031321000919