To Better Generate Organoids, What Can We Learn From Teratomas?

The genomic profile of animal models is not completely matched with the genomic profile of humans, and 2D cultures do not represent the cellular heterogeneity and tissue architecture found in tissues of their origin. Derived from 3D culture systems, organoids establish a crucial bridge between 2D ce...

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Bibliographic Details
Main Authors: Hongyu Li, Lixiong Gao, Jinlin Du, Tianju Ma, Zi Ye, Zhaohui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ESC
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.700482/full