A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA

A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA

Armor plate changes in sticklebacks are a classic example of repeated adaptive evolution. Previous studies identified ectodysplasin (EDA) gene as the major locus controlling recurrent plate loss in freshwater fish, though the causative DNA alterations were not known. Here we show that freshwater EDA...

Full description

Bibliographic Details
Main Authors: Natasha M O'Brown, Brian R Summers, Felicity C Jones, Shannon D Brady, David M Kingsley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-01-01
Series:eLife
Subjects:
recurrent mutation
Wnt signaling
skeletal development
ectodysplasin gene
enhancer
stickleback
Online Access:https://elifesciences.org/articles/05290

Internet

https://elifesciences.org/articles/05290

Similar Items