Leishmania infantum Virulence Factor A2 Protein: Linear B-Cell Epitope Mapping and Identification of Three Main Linear B-Cell Epitopes in Vaccinated and Naturally Infected Dogs

Leishmania infantum Virulence Factor A2 Protein: Linear B-Cell Epitope Mapping and Identification of Three Main Linear B-Cell Epitopes in Vaccinated and Naturally Infected Dogs

In Brazil, canine visceral leishmaniasis (CVL) is caused by Leishmania infantum, presenting a broad spectrum of clinical manifestations. Dogs are the main parasite reservoir in urban areas and canine cases precede human infection. Currently, A2 protein based Leish-Tec® vaccine is the only vaccine co...

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Bibliographic Details
Main Authors: Monique Paiva Campos, Fabiano Borges Figueiredo, Fernanda Nazaré Morgado, Alinne Rangel dos Santos Renzetti, Sara Maria Marques de Souza, Sandro Antônio Pereira, Rodrigo Nunes Rodrigues-Da-Silva, Josué Da Costa Lima-Junior, Paula Mello De Luca
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
canine visceral leishmaniasis
vaccines
A2 protein
serology test
epitope mapping
epitope prediction
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01690/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01690/full

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