Comprehensive proteome analysis of nasal lavage samples after controlled exposure to welding nanoparticles shows an induced acute phase and a nuclear receptor, LXR/RXR, activation that influence the status of the extracellular matrix

Comprehensive proteome analysis of nasal lavage samples after controlled exposure to welding nanoparticles shows an induced acute phase and a nuclear receptor, LXR/RXR, activation that influence the status of the extracellular matrix

Abstract Background Epidemiological studies have shown that many welders experience respiratory symptoms. During the welding process a large number of airborne nanosized particles are generated, which might be inhaled and deposited in the respiratory tract. Knowledge of the underlying mechanisms beh...

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Bibliographic Details
Main Authors: Neserin Ali, Stefan Ljunggren, Helen M. Karlsson, Aneta Wierzbicka, Joakim Pagels, Christina Isaxon, Anders Gudmundsson, Jenny Rissler, Jörn Nielsen, Christian H. Lindh, Monica Kåredal
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Clinical Proteomics
Subjects:
Chamber study
Welding fume particles
Nasal lavage
Effects
Proteomics
Mass spectrometry
Online Access:http://link.springer.com/article/10.1186/s12014-018-9196-y

Internet

http://link.springer.com/article/10.1186/s12014-018-9196-y

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