Mode of action and functional significance of 7alpha-hydroxypregnenolone stimulating locomotor activity

Previous studies over the past two decades have demonstrated that the brain and other nervous systems possess key steroidogenic enzymes and produces pregnenolone and other various neurosteroids in vertebrates in general. Recently, 7alpha-hydroxypregnenolone, a novel bioactive neurosteroid, was ident...

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Bibliographic Details
Main Authors: Shogo eHaraguchi, Masahiro eMatsunaga, Hubert eVaudry, Kazuyoshi eTsutsui
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-08-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00023/full