Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

Abstract Background SARS-CoV-2 is a RNA coronavirus responsible for the pandemic of the Severe Acute Respiratory Syndrome (COVID-19). RNA viruses are characterized by a high mutation rate, up to a million times higher than that of their hosts. Virus mutagenic capability depends upon several factors,...

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Bibliographic Details
Main Authors: Maria Pachetti, Bruna Marini, Francesca Benedetti, Fabiola Giudici, Elisabetta Mauro, Paola Storici, Claudio Masciovecchio, Silvia Angeletti, Massimo Ciccozzi, Robert C. Gallo, Davide Zella, Rudy Ippodrino
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Translational Medicine
Subjects:
SARS-CoV-2
COVID-19
Mutation
Drug resistance
RdRp
Europe
Online Access:http://link.springer.com/article/10.1186/s12967-020-02344-6

Internet

http://link.springer.com/article/10.1186/s12967-020-02344-6

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