Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors

Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors

Nucleocytoplasmic transport is mediated by nuclear pore complexes (NPCs) embedded in the nuclear envelope. About 30 different proteins (nucleoporins, nups) arrange around a central eightfold rotational axis to build the modular NPC. Nup188 and Nup192 are related and evolutionary conserved, large nuc...

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Bibliographic Details
Main Authors: Kasper R Andersen, Evgeny Onischenko, Jeffrey H Tang, Pravin Kumar, James Z Chen, Alexander Ulrich, Jan T Liphardt, Karsten Weis, Thomas U Schwartz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-06-01
Series:eLife
Subjects:
nucleocytoplasmic transport
macromolecular assemblage
Myceliophthora thermophila
Online Access:https://elifesciences.org/articles/00745

Internet

https://elifesciences.org/articles/00745

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