Regulation of the tumor suppressor PML by sequential posttranslational modifications
Posttranslational modifications (PTMs) regulate multiple biological functions of the PML (promyelocytic leukemia) protein and also the fission, disassembly and rebuilding of PML nuclear bodies (PML-NBs) during the cell cycle. Pathway-specific PML modification patterns ensure proper signal output fro...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-12-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00204/full |