Critical hubs of renal ischemia-reperfusion injury: endoplasmic reticulum-mitochondria tethering complexes

Abstract. Mitochondrial injury and endoplasmic reticulum (ER) stress are considered to be the key mechanisms of renal ischemia-reperfusion (I/R) injury. Mitochondria are membrane-bound organelles that form close physical contact with a specific domain of the ER, known as mitochondrial-associated mem...

Full description

Bibliographic Details
Main Authors: Huan-Huan Zhao, Qiu-Xia Han, Xiao-Nan Ding, Jing-Yao Yan, Qi Li, Dong Zhang, Han-Yu Zhu, Li-Shao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2020-11-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001091