Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation

Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation

Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS). Upregulation of ALR was observed in multiple forms of cancer, among them hepatocellular c...

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Bibliographic Details
Main Authors: Yaschar Kabiri, Anna Fuhrmann, Anna Becker, Luisa Jedermann, Carola Eberhagen, Ann-Christine König, Tiago Barros Silva, Fernanda Borges, Stefanie M. Hauck, Bernhard Michalke, Percy Knolle, Hans Zischka
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mitochondria
HCC
disulfide relay system
iron
heme
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.725474/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.725474/full

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