The LncRNA MIR503HG/miR-224-5p/TUSC3 Signaling Cascade Suppresses Gastric Cancer Development via Modulating ATF6 Branch of Unfolded Protein Response

The LncRNA MIR503HG/miR-224-5p/TUSC3 Signaling Cascade Suppresses Gastric Cancer Development via Modulating ATF6 Branch of Unfolded Protein Response

BackgroundUnfolded protein response (UPR)-mediated tumor-promoting functions have been identified in multiple cancers, and this study focused on investigating the role and molecular mechanisms of UPR in modulating gastric cancer (GC) pathogenesis.MethodsThe bioinformatics analysis was performed to e...

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Bibliographic Details
Main Authors: Han Lin, Jinge Wang, Tong Wang, Jiaming Wu, Peng Wang, Xiaoyan Huo, Jun Zhang, Huayang Pan, Yuying Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
unfolded protein response
gastric cancer
LncRNA MIR503HG
miR-224-5p
TUSC3
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.708501/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.708501/full

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