Comparison of the Pharmacological Effects of Paricalcitol and Doxercalciferol on the Factors Involved in Mineral Homeostasis

Vitamin D receptor agonists (VDRAs) directly suppress parathyroid hormone (PTH) mRNA expression. Different VDRAs are known to have differential effects on serum calcium (Ca), which may also affect serum PTH levels since serum Ca regulates PTH secretion mediated by the Ca-sensing receptor (CaSR). In...

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Bibliographic Details
Main Authors: J. Ruth Wu-Wong, Masaki Nakane, Gerard D. Gagne, Kristin A. Brooks, William T. Noonan
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2010/621687