Characterization of Receptor Binding Profiles of Influenza A Viruses Using An Ellipsometry-Based Label-Free Glycan Microarray Assay Platform

Characterization of Receptor Binding Profiles of Influenza A Viruses Using An Ellipsometry-Based Label-Free Glycan Microarray Assay Platform

A key step leading to influenza viral infection is the highly specific binding of a viral spike protein, hemagglutinin (HA), with an extracellular glycan receptor of a host cell. Detailed and timely characterization of virus-receptor binding profiles may be used to evaluate and track the pandemic po...

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Bibliographic Details
Main Authors: Yiyan Fei, Yung-Shin Sun, Yanhong Li, Hai Yu, Kam Lau, James P. Landry, Zeng Luo, Nicole Baumgarth, Xi Chen, Xiangdong Zhu
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Biomolecules
Subjects:
influenza A virus
glycans
binding profile
microarray
label-free
ellipsometry
biosensors
high-throughput
reaction kinetics
Online Access:http://www.mdpi.com/2218-273X/5/3/1480

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http://www.mdpi.com/2218-273X/5/3/1480

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