miR-203 regulates cell proliferation through its influence on Hakai expression.

Gene expression is potently regulated through the action of microRNAs (miRNAs). Here, we present evidence of a miRNA regulating Hakai protein. Hakai was discovered as an E3 ubiquitin-ligase that mediates the posttranslational downregulation of E-cadherin, a major component of adherens junctions in e...

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Bibliographic Details
Main Authors: Vanessa Abella, Manuel Valladares, Teresa Rodriguez, Mar Haz, Moisés Blanco, Nuria Tarrío, Pilar Iglesias, Luís A Aparicio, Angélica Figueroa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527564?pdf=render