BNT162b2 Vaccine Encoding the SARS-CoV-2 P2 S Protects Transgenic hACE2 Mice against COVID-19

BNT162b2 Vaccine Encoding the SARS-CoV-2 P2 S Protects Transgenic hACE2 Mice against COVID-19

BNT162b2 is a highly efficacious mRNA vaccine approved to prevent COVID-19. This brief report describes the immunogenicity and anti-viral protective effect of BNT162b2 in hACE2 transgenic mice. Prime-boost immunization with BNT162b2 elicited high titers in neutralizing antibodies against SARS-CoV-2,...

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Bibliographic Details
Main Authors: Rui-Ru Ji, Yajin Qu, Hua Zhu, Yumei Yang, Annette B. Vogel, Ugur Sahin, Chuan Qin, Aimin Hui
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Vaccines
Subjects:
SARS-CoV-2
COVID-19
mRNA vaccine
efficacy
immunogenicity
challenge study
Online Access:https://www.mdpi.com/2076-393X/9/4/324

Internet

https://www.mdpi.com/2076-393X/9/4/324

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