Targeting CA-125 Transcription by Development of a Conditionally Replicative Adenovirus for Ovarian Cancer Treatment

Targeting CA-125 Transcription by Development of a Conditionally Replicative Adenovirus for Ovarian Cancer Treatment

CA-125, encoded by the <i>MUC16</i> gene, is highly expressed in most ovarian cancer cells and thus serves as a tumor marker for monitoring disease progression or treatment response in ovarian cancer patients. However, targeting <i>MUC16</i>/CA-125 for ovarian cancer treatmen...

Full description

Bibliographic Details
Main Authors: Er Yue, Guangchao Yang, Yuanfei Yao, Guangyu Wang, Atish Mohanty, Fang Fan, Ling Zhao, Yanqiao Zhang, Tamara Mirzapoiazova, Tonya C. Walser, Lorna Rodriguez-Rodriguez, Yuman Fong, Ravi Salgia, Edward Wenge Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
conditionally replicative oncolytic adenovirus
ovarian cancer
CA-125
<i>MUC16</i>
transcription
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/13/17/4265

Internet

https://www.mdpi.com/2072-6694/13/17/4265

Similar Items