Behavioral Abnormalities in Knockout and Humanized Tau Mice

Microtubule-associated protein tau assists in stabilizing microtubules and has been particularly implicated in Alzheimer's disease (AD). Given the importance of tau to AD pathogenesis and therapies, it is important to understand non-classic physiological functions for this protein inside and ou...

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Bibliographic Details
Main Authors: Rafaella Araujo Gonçalves, Nadeeja Wijesekara, Paul E. Fraser, Fernanda G. De Felice
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00124/full