Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Understanding the genetic regulation of organ structure is a fundamental problem in developmental biology. Here, we use egg-producing structures of insect ovaries, called ovarioles, to deduce systems-level gene regulatory relationships from quantitative functional genetic analysis. We previously sho...

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Bibliographic Details
Main Authors: Tarun Kumar, Leo Blondel, Cassandra G Extavour
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/54082