miR-190 enhances endocrine therapy sensitivity by regulating SOX9 expression in breast cancer

miR-190 enhances endocrine therapy sensitivity by regulating SOX9 expression in breast cancer

Abstract Background Breast cancer is the most common cancer among women worldwide, and approximately 70% of breast cancers are hormone receptor-positive and express estrogen receptor-α (ERα) or/and progesterone receptor. Therapies targeting ERα have been successfully used in patients with ERα+ breas...

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Bibliographic Details
Main Authors: Yue Yu, Wen Yin, Zhi-Hao Yu, Yan-Jun Zhou, Jiang-Rui Chi, Jie Ge, Xu-Chen Cao
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Breast cancer
Endocrine therapy
Wnt/β-catenin signaling
miR-190
SOX9
ZEB1
Online Access:http://link.springer.com/article/10.1186/s13046-019-1039-9

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http://link.springer.com/article/10.1186/s13046-019-1039-9

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