Deletion of ASK1 Protects against Hyperoxia-Induced Acute Lung Injury.

Deletion of ASK1 Protects against Hyperoxia-Induced Acute Lung Injury.

Apoptosis signal-regulating kinase 1 (ASK1), a member of the MAPK kinase kinase kinase (MAP3K) family, is activated by various stimuli, which include oxidative stress, endoplasmic reticulum (ER) stress, calcium influx, DNA damage-inducing agents and receptor-mediated signaling through tumor necrosis...

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Bibliographic Details
Main Authors: Jutaro Fukumoto, Ruan Cox, Itsuko Fukumoto, Young Cho, Prasanna Tamarapu Parthasarathy, Lakshmi Galam, Richard F Lockey, Narasaiah Kolliputi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4726536?pdf=render

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http://europepmc.org/articles/PMC4726536?pdf=render

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