Quantitative analysis of protein-protein interactions and post-translational modifications in rare immune populations

Rare immune or stem cell populations are difficult to quantitatively analyze for protein-protein interactions or post-translational modifications despite advances in proteomics. Here the authors develop proximity ligation imaging cytometry for high-resolution detection at a single cell level.

Bibliographic Details
Main Authors: Ayelet Avin, Maayan Levy, Ziv Porat, Jakub Abramson
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01808-6