Cholesterol depletion disorganizes oocyte membrane rafts altering mouse fertilization.

Cholesterol depletion disorganizes oocyte membrane rafts altering mouse fertilization.

Drastic membrane reorganization occurs when mammalian sperm binds to and fuses with the oocyte membrane. Two oocyte protein families are essential for fertilization, tetraspanins and glycosylphosphatidylinositol-anchored proteins. The firsts are associated to tetraspanin-enriched microdomains and th...

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Bibliographic Details
Main Authors: Jorgelina Buschiazzo, Come Ialy-Radio, Jana Auer, Jean-Philippe Wolf, Catherine Serres, Brigitte Lefèvre, Ahmed Ziyyat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3636221?pdf=render

Internet

http://europepmc.org/articles/PMC3636221?pdf=render

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