Current status of antibody-drug conjugate bioanalysis

Antibody-drug conjugate (ADC) consists of a cytotoxic drug covalently bound to a monoclonal antibody via a linker. Because of the complexity of ADC structure unique bioanalytical strategies are needed to identify, characterize and quantify the ADC species most relevant to safety and efficacy. ADC bi...

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Bibliographic Details
Main Author: Jian Wang
Format: Article
Language:English
Published: Betasciencepress Publishers 2017-04-01
Series:Journal of Applied Bioanalysis
Subjects:
Online Access:https://doi.org/10.17145/jab.17.004