Progress toward resistance mechanism to epidermal growth factor receptor tyrosine kinase inhibitor

The EGFR signaling pathway plays an important role in the occurrence and development of many malignant tumors. It has become a hot spot in the treatment of advanced cancer. At present, the small molecule epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), has been shown to advance...

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Bibliographic Details
Main Authors: Zhang Lingling, Zhang Xiaoxue, Zhao Liang
Format: Article
Language:English
Published: De Gruyter 2016-01-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2016-0056