Krüppel-like Factor 4 Inhibits Tumorigenic Progression and Metastasis in a Mouse Model of Breast Cancer

Krüppel-like factor 4 (KLF4) is a zinc finger transcription factor that functions as an oncogene or tumor suppressor in a highly tissue-specific cell-dependent manner. However, its precise role in breast cancer and metastasis remains unclear. Here, we show that transient adenoviral expression of KL...

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Bibliographic Details
Main Authors: Jennifer L Yori, Darcie D Seachrist, Emhonta Johnson, Kristen L Lozada, Fadi W Abdul-Karim, Lewis A Chodosh, William P Schiemann, Ruth A Keri
Format: Article
Language:English
Published: Elsevier 2011-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800242