The ZEB1 transcription factor is a novel repressor of adiposity in female mice.

BACKGROUND:Four genome-wide association studies mapped an "obesity" gene to human chromosome 10p11-12. As the zinc finger E-box binding homeobox 1 (ZEB1) transcription factor is encoded by the TCF8 gene located in that region, and as it influences the differentiation of various mesodermal...

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Bibliographic Details
Main Authors: Jessica N Saykally, Soner Dogan, Margot P Cleary, Michel M Sanders
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2794530?pdf=render