Expression of co-stimulatory molecules CD80 and CD86 is altered in CD14 + HLA-DR + monocytes from patients with Chagas disease following induction by Trypanosoma cruzi recombinant antigens

Expression of co-stimulatory molecules CD80 and CD86 is altered in CD14 + HLA-DR + monocytes from patients with Chagas disease following induction by Trypanosoma cruzi recombinant antigens

Abstract INTRODUCTION The relationships between monocytes and lymphocytes through MHC class II molecules and costimulatory, are of utmost importance for the production of an efficient immune response. In this work, we assessed the expression of surface molecules CD80 and CD86 on CD14+HLA-DR+ monoc...

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Bibliographic Details
Main Authors: Ana Karine de Araújo Soares, Patrícia Areias Feitosa Neves, Maria da Glória Aureliano de Melo Cavalcanti, Sílvia Martins Marinho, Wilson de Oliveira Júnior, Joelma Rodrigues de Souza, Virginia Maria Barros de Lorena, Yara de Miranda Gomes
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Chagas disease
Immune response
Recombinant antigens
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000500632&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000500632&lng=en&tlng=en

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