Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients.

Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients.

Naturally acquired blood-stage infections of the malaria parasite Plasmodium falciparum typically harbour multiple haploid clones. The apparent number of clones observed in any single infection depends on the diversity of the polymorphic markers used for the analysis, and the relative abundance of r...

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Bibliographic Details
Main Authors: Timothy Robinson, Susana G Campino, Sarah Auburn, Samuel A Assefa, Spencer D Polley, Magnus Manske, Bronwyn MacInnis, Kirk A Rockett, Gareth L Maslen, Mandy Sanders, Michael A Quail, Peter L Chiodini, Dominic P Kwiatkowski, Taane G Clark, Colin J Sutherland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3154926?pdf=render

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http://europepmc.org/articles/PMC3154926?pdf=render

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