Reversing Postcardiopulmonary Bypass Associated Cognitive Dysfunction Using k-Opioid Receptor Agonists to Regulate Microglial Polarization via the NLRP3/Caspase-1 Pathway

Reversing Postcardiopulmonary Bypass Associated Cognitive Dysfunction Using k-Opioid Receptor Agonists to Regulate Microglial Polarization via the NLRP3/Caspase-1 Pathway

Cardiopulmonary bypass (CPB) is mainly used during cardiac surgeries that treat ischemic, valvular, or congenital heart disease and aortic dissections. The disorders of central nervous system (CNS) that occur after cardiopulmonary bypass are attracting considerable interest. Postoperative neurocogni...

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Bibliographic Details
Main Authors: Pei Song, Zhuo Yi, Yiji Fu, Dandan Song, Keyan Chen, Jingjing Zheng, Yingjie Sun, Yugang Diao
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Healthcare Engineering
Online Access:http://dx.doi.org/10.1155/2021/3048383

Internet

http://dx.doi.org/10.1155/2021/3048383

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